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After the door closes start walking to the left, the bone pillar will fire two fireballs your direction. Once you just past the first candle you jump and throw a holy water (which will land on the bone pillar) and then jump again over the second fireball. Once past the pillar jump and throw a holy water at the base of the stairs to take care of the red skeleton.

Walk up the stairs until Simon's knee almost touches the bone pillar and throw a holy water while holding up. Simon should throw the water and pass through the pillar. Your other options are to take the damage (if you have the health) or to whip down the pillar.

Walking to the right you'll encounter two red skeletons, whip or jump over them, if you need health there is meat in the walk after the stairs to the next screen.

The hallway before death is one of the hardest in the game without holy water but with the water there is a pattern of moving to left and then jumping and throwing the water so it lands on the axe knights, stunning them in place, allowing Simon to walk through them and also killing them. The only thing to worry about then is the medusa heads and as long and you keep moving right you should be able to jump over them without any issue.